Brian,
I've had the Wacom working with Kyma and another software, but my working solution requires Kyma and Max/MSP open simultaneously. In Max/MSP, the s2m.wacom OR s2m.wacomtouch (for finger control) object does a nice job of harnessing the Wacom for use with OSC messages. I recently performed a piece by Wang Chi where she does this specifically. She used s2m.wacomtouch in Max (sending OSC messages to Kyma), and she still had use of Kyma native pen controls, like !PenX !PenYTilt etc. I'm happy to correspond off forum. jon@jpbellona.com