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We are working with Wacom on this issue. Until this is resolved, we recommend using the Wacom driver:
6.3.15-3
If that driver does not work with your tablet, then use
6.3.23-3
For more about this issue, please see the last answer in this thread: http://kyma.symbolicsound.com/qa/3019/wacom-intuos-pro-m-not-working-driver-6-3-25-2?show=3019#q3019
I just installed the latest Win10 driver 6.3.27-2(for Mac too) from here and it works:
http://www.wacom.com/en/support/product-support/drivers